Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors

摘要

We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample fluid and bind to the sensor surface with biological specificity. The surface-bound nanoparticles are then detected using frustration of an evanescent field. In the current paper we elaborate on the polymer waveguides which are used to generate a well-defined optical field for nanoparticle detection. © (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.